BRILLIANT CRESYL BLUE

Additional information

Size

1000 ml, 2500 ml

A supravital stain used for counting reticulocytes.

Application: Blood smears examination for reticulocytes. Brilliant cresol blue is more used in hematology laboratories than in histology Laboratories it’s invaluable for the staining of reticulocytes whereas its use in histology is limited to vital staining. Reticulocytes are juvenile red cells, which contain remnants of basophilic ribonucleoproteins. This material reacts with brilliant cresol blue to form a bluish black precipitate of granules or filaments. The most immature reticulocytes have the largest amount of profitable material. In the least immature only a few dots or short strands are seen. As the number of reticulocytes in the peripheral blood is a measure of erythropoietin activity, a reticulocyte count is one of the essential procedures of diagnostic hematology.